A blog by two chemists working in chemistry and chemical biology
Showing posts with label viva survivor. Show all posts
Showing posts with label viva survivor. Show all posts
Tuesday, 29 January 2013
George Orwell's rules on writing: applicable to science?
The 65th anniversary of George Orwell’s 1984 this
year and the BBC is putting on many programs discussing the work of the great
author. Orwell had some very strong
views on how things should be written and wrote an essay on the subject about 6
rules that he thought should be at the centre of any piece of writing, so can
they be applied successfully to science writing?
Wednesday, 23 January 2013
Viva Survivor: Baldwin's rules
This is the first of the basic science posts we will be running about once a week; first up is Baldwin's rules (or guidelines as many prefer), for more detail look here.
Baldwin’s rules are empirical observations of possible
cyclisation reactions, classified according to the size of the ring being formed, the
nature of the electrophilic portion of the molecule and whether the bonds are
broken inside or outside of the ring.
Although the based on empirical observation they use stereochemical reasoning including orbital overlap and the preferred
angle of attack of a nucleophile. Because they are essentially empirical they are not really rules
in the Woodwood—Hoffman sense of the word, but should be thought of as
guidelines; there are exceptions!
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